Recruitment
CTTI Releases 2017 Annual Report: One Decade of Impact. One Vision Ahead.
CTTI’s 2017 Annual Report, released today, celebrates a decade of CTTI impact and highlights our activities and accomplishments over the past year. The report includes reflections from past and present CTTI leaders, case studies on the use of CTTI recommendations and resources, and a glimpse into what lies ahead for CTTI and the clinical trials enterprise.
Since its founding in 2007, CTTI has completed more than 25 projects with the aim of increasing the quality and efficiency of clinical trials. The resulting recommendations were downloaded more than 26,000 times over the past year.
CTTI issued five new sets of recommendations in 2017, many of which draw on recent advances in technology and data sciences to bring about improvements for clinical trials. Read the report to learn more about our latest recommendations and resources, which offer:
- Practical guidance for using mobile technology to develop viable novel endpoints for clinical trials.
- Best practices for assessing and designing registries for use in clinical trials so that the data can meet expectations for FDA review of new products.
- Actions that can be taken to strengthen the investigator site community and create an environment that sustains long-term investigator engagement.
- Guidance on planning for and making decisions about pregnancy testing in potential trial participants.
- Suggested ways to address the unique challenges of conducting pediatric antibacterial trials.
As described in the report, these recommendations and resources are being implemented by organizations across the clinical trial spectrum, including IQVIA, monARC Bionetworks, and the Pulmonary Fibrosis Foundation.
As we reflect on the past year—and the past decade—we are grateful for the engagement and commitment of our members, who ensure that we continue to address the latest trends, top barriers, and leading opportunities in clinical research.
CTTI Article in Contemporary Clinical Trials Outlines Framework for Successful Trial Recruitment
A CTTI article outlining a framework for successful clinical trial recruitment planning was recently published in Contemporary Clinical Trials.
While patient recruitment is widely recognized as a key determinant of success for clinical trials, a substantial number of trials still fail to reach their recruitment goals. To address this issue, CTTI convened a project team to examine the challenges and develop actionable, evidence-based recommendations for improving recruitment planning.
These recommendations propose an upstream approach to recruitment planning, focusing on factors that affect recruitment earlier in clinical trial development. The recommendations focus on three essential areas in particular:
- Trial design and protocol development: Identifying all stakeholders, ensuring the relevance of the scientific question, limiting complexity, having realistic eligibility criteria, and optimizing data collection.
- Trial feasibility and site selection: Conducting evidence-based feasibility analysis, having realistic metrics and milestones, developing an adequate budget and resources, ensuring appropriate site selection, and engaging in suitable performance monitoring.
- Communication planning: Identifying where participants seek treatment, developing and testing tailored messages, developing creative material and selecting appropriate delivery channels, having a realistic budget, monitoring and evaluating process and performance, and embedding recruitment intervention studies and sharing results.
CTTI also developed resources to help facilitate adoption of the recommendations, including methods for identifying stakeholders and considerations for patient-reported outcomes. Together, the recommendations and tools are designed to guide efforts in clinical trial recruitment planning and identify areas for continual improvement.
CTTI Shares Tools for Improving Trials in 2 Presentations at SCOPE Summit
This year’s SCOPE Summit, taking place January 24-26, 2017, in Miami, FL, will feature three presentations on CTTI recommendations for adopting quality by design, patient engagement, and recruitment in clinical trials. SCOPE, the Summit for Clinical Ops Executives, is focused on issues around clinical trial best practices, and attendees include industry leaders from over 500 organizations. CTTI looks forward to the opportunity to engage with decision-makers across the clinical trial enterprise to improve clinical trial planning and management.
Don’t miss our informative sessions with actionable takeaways:
Presentation: Moving Recruitment Planning Upstream to Reduce Barriers to Participation: Recommendations from the CTTI Recruitment Planning Project
Presenter: Beth Mahon, Janssen Research and Development
Date & Time: Tuesday, January 24 from 11:15 – 11:40 AM ET
Description: Learn the importance of proactivity in clinical trials planning in order to reduce participation barriers. This session will describe recommendations from CTTI’s Recruitment Project, which provide a framework for strategic recruitment planning that begins during the trial design and development process.
Presentation: Patient Group Engagement in Clinical Trials: Best Practices for Best Value
Presenter: David Leventhal, Pfizer, Inc. and Ken Getz, Tufts Center for the Study of Drug Development
Date & Time: Wednesday, January 25 from 5:20 – 5:45 PM ET
Description: Learn to apply actionable recommendations for establishing strong, active patient group engagement during all phases of the research and development life cycle. We’ll also share our net present value model that helps to quantify the value, including financial return on investment, of patient engagement. These tools and best practices resulted from CTTI’s Patient Groups & Clinical Trials Project.
Happy Holidays from CTTI – Gifts you can use
If quality, efficient trials are on your wish list, we’ve got you covered.
CTTI’s latest recommendations and tools:
- Meet your recruitment goals with our tools for strategic recruitment planning
- Improve the quality of trial oversight with our best practices for data monitoring committees
- Apply our approaches to streamline the development of antibacterial drugs
In 2016, there were over 30,000 downloads from the CTTI website. Popular favorites include our evidence-based recommendations on trial quality, informed consent, and patient group engagement.
By engaging all stakeholders to develop actionable solutions, we are creating a better system for clinical trials. Thank you to all of our members and contributors for their efforts this past year, and best wishes for a successful 2017!
Recording Now Available: Webinar on Improving Clinical Trial Recruitment
On May 19, 2016, CTTI hosted a webinar on moving recruitment planning upstream to reduce barriers to clinical trial participation. This webinar was the official unveiling of CTTI’s new recommendations and tools resulting from the Recruitment Project. We are now pleased to share the recording from this webinar, in which you can learn more about:
- A holistic approach that integrates strategic recruitment planning throughout the entire clinical trial process, beginning with study design and development
- Ways to identify and engage all relevant stakeholders throughout recruitment planning to prevent downstream recruitment challenges
- Recommendations for trial feasibility, site selection, and developing strategic recruitment communication plans
- New tools available to aid in strategic recruitment planning
The slides and responses from the webinar’s Q&A session are also available for download.
We encourage you to share these resources with your colleagues in the clinical trials enterprise.
To view recordings of other CTTI webinars, CLICK HERE.