CTTI Homepage

CTTI Homepage

Modernizing Trials Together

CTTI is the one member-based organization that brings together experts from every facet of the clinical trials enterprise as equal voices to solve the most complex challenges in clinical trials. Through our collaborative and innovative efforts, we are transforming the landscape of clinical trials for participants, researchers, and the public.

CTTI Impact

Disease Progression Modeling

CTTI is advancing the use of disease progression modeling in clinical trials by promoting consistent, data-driven strategies that optimize trial design, enhance decision-making, and accelerate the development of safe, effective treatments for patients.

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CTTI Best Practices & Innovations

  • SafetySafety
    Ensuring the safety and protection of our study participants is ...

  • Patient EngagementPatient Engagement
    Engaging patients and patient organizations as partners early and often ...

  • Ensuring QualityEnsuring Quality
    “Quality” in clinical trials is defined as the absence of ...

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CTTI Spotlight

Inside the State of Clinical Trials

On May 22, CTTI brought together 150 clinical trials leaders, patients, policy influencers, and researchers in Washington, D.C., for a dynamic and solutions-focused meeting on the state of clinical trials. The event centered on identifying key barriers to progress across the research enterprise and collaboratively exploring actionable solutions. Through interactive breakout sessions, attendees engaged deeply with the five pillars of CTTI’s Transforming Trials 2030 vision, guided by more than 25 expert facilitators from across the field.

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CTTI Happenings

Webinars |

Artificial Intelligence in Drug & Biological Product Development Hybrid Public Workshop 2025

Access the agenda, slides, and recording from the 2025 AI in Drug and Biological Product Development Hybrid Public Workshop.
CTTI News |

FDA, CTTI Convening 2025 Hybrid Public Workshop on Artificial Intelligence in Drug & Biological Product Development

Registration is now open for the second Hybrid Public Workshop on Artificial Intelligence in Drug and Biological Product Development, hosted by the U.S. Food and Drug Administration in collaboration with...
CTTI News |

CTTI Releases New Recommendations to Guide Use of Disease Progression Modeling in Medical Product Development

CTTI today released new recommendations to support the effective use of disease progression modeling (DPM) in medical product development.
CTTI News |

Optimizing Flexibility and Data Quality in Clinical Trials: Bringing Clarity to DIA Global 2025

At this year’s DIA Global Annual Meeting, Lindsay Kehoe, senior project manager at the Clinical Trials Transformation Initiative, chaired a panel under Track 8 – R&D Quality and Compliance –...

CTTI Work

CTTI Projects

The need for better clinical trials has never been clearer. CTTI unites experts across the clinical trials enterprise to identify challenges, exchange ideas, and develop actionable solutions. Through a collaborative, research-driven approach, CTTI creates evidence-based recommendations and tools that enhance trial quality and efficiency today while advancing a bold vision for the future: Transforming Trials 2030.

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CTTI Members

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CTTI Vision

A Bold Vision for 2030

CTTI is driving a future where clinical trials are more efficient, inclusive, and impactful. As we head toward 2030, we’re setting the course for transformation—championing forward-thinking practices, fostering collaboration, and shaping a research ecosystem that delivers better, faster, and more accessible evidence to improve health for all. 

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