In an effort to characterize the U.S. clinical trials enterprise, CTTI’s State of Clinical Trials Project set out to facilitate the analyses of data in ClinicalTrials.gov, a registry of human clinical research studies hosted by the U.S. National Institutes of Health (NIH) in collaboration with the FDA. The result of this project was the Aggregate Analysis of ClincalTrials.gov (AACT) Database, a restructured and reformatted relational database developed using publicly available and downloadable data from ClinicalTrials.gov. Since the original AACT was created in 2010, we’ve continued to regularly issue updated versions of the database.

The latest version of the AACT Database is now available on the CTTI website, along with the supporting documents. This dataset reflects data downloaded from ClinicalTrials.gov in March 2014. To assist users with interpretation of the data, a high level dictionary and a points to consider document are also located on the CTTI website. Previous versions of AACT are available as well.