JAMA Publishes CTTI’s Recommendations for Data Monitoring Committees

Posted on by Lorri Bingham

New PublicationsAn article describing key points from CTTI’s Recommendations for Data Monitoring Committees (DMCs) appears in this week’s edition of JAMA. As independent bodies able to review accumulating data for ongoing clinical trials, DMCs fulfill a unique and vital role in ensuring the scientific integrity and safety of clinical trials.

The article details the following:

  • The unequivocal need for DMCs to review unmasked data
  • The importance of DMCs reviewing safety and efficacy data together
  • Appropriate qualifications for DMC members

With the growing use of DMCs for trial oversight, these evidence-based best practices for DMC establishment and conduct can help ensure proper DMC functioning to fulfill their mission. CTTI is pleased to see these recommendations reach a broad audience and is encouraging widespread implementation.

View CTTI’s complete recommendations for additional consensus-driven best practices for DMCs.

To learn more about CTTI’s DMCs Project, CLICK HERE.