Peripheral Vascular Disease (PVD) poses a growing public health concern, particularly for the aging American population. While a high prevalence of vascular disease exists, and therapeutic advances have been made in this area, a systematic overview of the clinical trials portfolio for PVD has not been done, until recently.

A new Circulation publication, titled Clinical Trials in Peripheral Vascular Disease: Pipeline and Trial Designs: An Evaluation of the ClinicalTrials.gov Database, utilized the CTTI-created AACT Database, a searchable relational database of content from ClinicalTrials.gov. The AACT Database allowed researchers to analyze interventional trials registered in ClinicalTrials.gov from October 2007 through September 2010 (n=40,970).

The author’s conclude,

PVD studies represent a small group of trials registered in ClinicalTrials.gov, despite the high prevalence of vascular disease in the general population. This low number, compounded by the decreasing number of PVD trials in the United States, is concerning and may limit the ability to inform current clinical practice of patients with PVD.*

To view the article online, CLICK HERE.

*Source: Sumeet Subherwal, Manesh R. Patel, Karen Chiswell, Beth A. Tidemann-Miller, W. Schuyler Jones, Michael S. Conte, Christopher J. White, Deepak L. Bhatt, John R. Laird, William R. Hiatt, Asba Tasneem, and Robert M. Califf, “Clinical Trials in Peripheral Vascular Disease: Pipeline and Trial Designs: An Evaluation of the ClinicalTrials.gov Database,” Circulation, (Sept 19 2014).