Site Planning

Site Planning

Site staff and investigators are on the front lines, directly interacting with participants and ensuring protocol adherence. From recruiting and retaining participants to managing complex regulatory requirements and ensuring data accuracy, their efforts are the heart of clinical research, and they need the right support to do their jobs well.

Use CTTI’s recommendations to boost your investigator and site support, ultimately optimizing your trial’s execution and conduct, improving site budget and contract negotiations, and helping sponsors strengthen the community of engaged site investigators.

Topic Resources

Site Planning | Expert Meetings

Assessing U.S. Clinical Trials Site Capacity and Readiness for Public Health Emergencies​

View materials from the July 2025 expert meeting.

Site Planning

Collective Strategies to Enhance Proportionate Enrollment

The Collective Strategies to Enhance Proportionate Enrollment project focuses on improving accountability, clarity, and communication across clinical trials partner groups to support more effective recruitment, enrollment, and retention practices. This...

Site Planning | CTTI News

CTTI Leads Discussion on Digital Health Trials at ETH Digital Biomarkers Summit

In November 2024, Lindsay Kehoe, senior project manager at CTTI, presented at the Digital Biomarkers Summit held at ETH Zurich.

Site Planning | CTTI News

New Publication Shares Findings & Recommendations for Embedding Clinical Trial Elements into Routine Clinical Practice

A new CTTI publication published in the Journal of Clinical and Translational Science highlights the qualitative research findings that informed recommendations to facilitate the integration of clinical trials into clinical practice.

Site Planning | Press Releases

Investigator Training Efficiencies Highlighted in New CTTI GCP Recommendations

The Clinical Trials Transformation Initiative (CTTI) has announced recommendations to streamline Good Clinical Practice (GCP) training of investigators who participate in clinical trials.

Site Planning | Press Releases

CTTI Offers Path Forward for Using Decentralized Clinical Trials

The Clinical Trials Transformation Initiative (CTTI) will unveil new recommendations to speed the use of decentralized clinical trials (DCTs)—trials run through telemedicine and mobile health care providers—today at the DPharm:...

Site Planning | Press Releases

CTTI Takes on Site Investigator Turnover in New Recommendations

The Clinical Trials Transformation Initiative (CTTI) will unveil new recommendations aimed at reducing high rates of turnover among U.S. clinical trial site investigators at the Society for Clinical Research Sites...

Site Planning | Press Releases

Conducting Multi-Center Trials: New Recommendations and Tool for Research

A collaborative research team established by the Clinical Trials Transformation Initiative (CTTI) created a new tool and recommendations to improve the efficiency and quality of multi-center clinical trials.

Site Planning | Press Releases

CTTI Launches New Online Digital Health Trials Hub

Today the Clinical Trials Transformation Initiative (CTTI) announced a new online Digital Health Trials Hub featuring enhanced recommendations and additional resources.

Site Planning | Press Releases

CTTI Releases New Recommendations and Resources for Using Real-World Data to Plan Trial Eligibility Criteria and Recruit Participants

During a public webinar today, the Clinical Trials Transformation Initiative (CTTI) will release new recommendations and resources on how to use real-world data (RWD) to evaluate trial eligibility criteria and...

DHT sub topics

Formats

CTTI Project

Stage of Trial