CTTI Leading
Advancing Innovative Solutions
This year, CTTI’s project teams addressed critical quality and efficiency challenges, from streamlining trial design to improving coordination and readiness across clinical trial sectors. With a common-sense ‘totality of evidence’ approach, CTTI is co-creating a research ecosystem that delivers better, faster, and more accessible evidence to improve health for all.
CTTI Community
Convening For Impact
In 2025, CTTI focused on bringing together leaders, patients, and partners for a series of high-impact convenings, including the inaugural State of Clinical Trials meeting, two salon dinners, the fall Steering Committee meeting, and a second AI convening with the FDA. Across these forums, participants tackled urgent challenges and opportunities in clinical research, from real-world data and decentralized models to AI integration, safety reporting, and regulatory modernization. Given evolving national priorities and rapidly advancing technological capabilities, we focused on creating connections across organizations and disciplines to spark new ideas and enhance collective learning.
CTTI Directions
Looking Ahead
In the year ahead, CTTI’s work will be guided by key questions that define the future of evidence generation: How will AI/ML reshape clinical development? How can every involved party accelerate uptake of common-sense regulatory flexibilities? How do we design studies that satisfy country-level enrollment expectations, maintain sufficient generalizability, and still go fast? By confronting these critical and urgent questions together, CTTI members and the broader enterprise are charting the path to a modern evidence generation system.
Driving Change Across Clinical Trials
Since 2007, CTTI has transformed the clinical trials landscape. Through comprehensive recommendations, practical tools, insightful case studies, and impactful publications and presentations, we continue to drive innovation and improve accessibility across the clinical research enterprise.
